Reactome | FLT3LG dimer binds FLT3

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10065965
displayName	FLT3LG dimer binds FLT3
eventOf	[Pathway:R-MMU-9607240] FLT3 Signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-8854736] FLT3LG dimer:FLT3 binds FLT3 - Mus musculus
inferredFrom	[Reaction:R-HSA-6786789] FLT3LG dimer binds FLT3 - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-6786756] FLT3 [plasma membrane] [Complex:R-MMU-8854740] FLT3LG dimer [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	FLT3LG dimer binds FLT3
output	[Complex:R-MMU-6786754] FLT3LG dimer:FLT3 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-6786789
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-9607240] FLT3 Signaling
(precedingEvent)	[Reaction:R-MMU-8854736] FLT3LG dimer:FLT3 binds FLT3
(inferredTo)	[Reaction:R-HSA-6786789] FLT3LG dimer binds FLT3

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