Reactome | MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10065881] DNA-directed DNA polymerase activity of MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-MMU-6786166] Translesion synthesis across unhooked ICL by POLN - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10065878
displayName	MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm]
hasComponent	[Complex:R-MMU-6786151] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-6786153] Poln [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-6786156] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm] - Homo sapiens
maxDepth	6
name	MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN
producedByEvent	[Reaction:R-MMU-6786155] POLN binds ICL-DNA - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-6786156
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-MMU-6786166] Translesion synthesis across unhooked ICL by POLN
(physicalEntity)	[CatalystActivity:10065881] DNA-directed DNA polymerase activity of MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm]
(inferredTo)	[Complex:R-HSA-6786156] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:Unhooked ICL-DNA:POLN [nucleoplasm]
(output)	[Reaction:R-MMU-6786155] POLN binds ICL-DNA

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