Reactome | HJURP:CENPA complex localizes to the centromere

Schema > Reaction > Entries

HJURP:CENPA complex localizes to the centromere Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10020494
displayName	HJURP:CENPA complex localizes to the centromere
eventOf	[Pathway:R-MMU-606279] Deposition of new CENPA-containing nucleosomes at the centromere - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-606326] HJURP:CENPA complex localizes to the centromere - Homo sapiens
input	[Complex:R-MMU-606342] CCAN:DNA:CASC5:Mis18 complex [nucleoplasm] [Complex:R-MMU-606319] HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	HJURP:CENPA complex localizes to the centromere
output	[Complex:R-MMU-606282] CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA:H4 [nucleoplasm]
precedingEvent	[Reaction:R-MMU-606349] Mis18 complex binds the centromere - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-606326
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-606279] Deposition of new CENPA-containing nucleosomes at the centromere
(inferredTo)	[Reaction:R-HSA-606326] HJURP:CENPA complex localizes to the centromere

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