Reactome | DNA Damage Recognition in GG-NER

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DNA Damage Recognition in GG-NER Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10101323
displayName	DNA Damage Recognition in GG-NER
eventOf	[Pathway:R-MMU-5696399] Global Genome Nucleotide Excision Repair (GG-NER) - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-MMU-5696395] Formation of Incision Complex in GG-NER - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:25103] nucleotide-excision repair, DNA damage recognition
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-5691004] XPC binds RAD23 and CETN2 - Mus musculus [Reaction:R-MMU-5691006] XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site - Mus musculus [Reaction:R-MMU-6782943] UV-DDB ubiquitinates XPC - Mus musculus [Reaction:R-MMU-5696664] PARP1 or PARP2 binds DDB2 at GG-NER site - Mus musculus [Reaction:R-MMU-5696655] PARP1 or PARP2 PARylates DDB2 and autoPARylates - Mus musculus
inferredFrom	[Pathway:R-HSA-5696394] DNA Damage Recognition in GG-NER - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	DNA Damage Recognition in GG-NER
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-5696394
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Pathway:R-MMU-5696395] Formation of Incision Complex in GG-NER
(hasEvent)	[Pathway:R-MMU-5696399] Global Genome Nucleotide Excision Repair (GG-NER)
(inferredTo)	[Pathway:R-HSA-5696394] DNA Damage Recognition in GG-NER