Reactome | Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA

Schema > Reaction > Entries

Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10062337] fatty acyl-CoA hydrolase activity of Cytosolic ACOTs, THEM4 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10062343
displayName	Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA
eventOf	[Pathway:R-MMU-77289] Mitochondrial Fatty Acid Beta-Oxidation - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:8047] acyl-CoA metabolic process
inferredFrom	[Reaction:R-HSA-5690043] Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [DefinedSet:R-ALL-5690044] MCFA-CoA, LCFA-CoA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA a medium-chain fatty acyl-CoA + H2O => a medium-chain fatty acid + CoA + H(+) a long-chain fatty acyl-CoA + H2O => a long-chain fatty acid + CoA + H(+)
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [DefinedSet:R-ALL-5690064] MCFA, LCFA [cytosol]
regulatedBy	[PositiveRegulation:10062344] Positive regulation by 'PCTP [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5690043
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-77289] Mitochondrial Fatty Acid Beta-Oxidation
(inferredTo)	[Reaction:R-HSA-5690043] Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA

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