Reactome | GRB2-1:SOS1 binds p-Y-SHC

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10060979
displayName	GRB2-1:SOS1 binds p-Y-SHC
eventOf	[Pathway:R-MMU-167044] Signalling to RAS - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5685366] GRB2-1:SOS1 binds p-Y-SHC - Homo sapiens
input	[Complex:R-MMU-109797] GRB2-1:SOS1 [cytosol] [DefinedSet:R-MMU-167016] p-Y-SHC [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GRB2-1:SOS1 binds p-Y-SHC
output	[Complex:R-MMU-5685367] GRB2-1:SOS1:p-Y-SHC [cytosol]
precedingEvent	[Reaction:R-MMU-109813] GRB2-1 binds SOS1 - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5685366
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-167044] Signalling to RAS
(inferredTo)	[Reaction:R-HSA-5685366] GRB2-1:SOS1 binds p-Y-SHC

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