Reactome | ATG10:ATG12 binds ATG5

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10060263
displayName	ATG10:ATG12 binds ATG5
eventOf	[Pathway:R-MMU-1632852] Macroautophagy - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-5683588] ATG10 transfers ATG12 from ATG10 to ATG5 - Mus musculus
inferredFrom	[Reaction:R-HSA-5682010] ATG10:ATG12 binds ATG5 - Homo sapiens
input	[Complex:R-MMU-5682644] ATG12:GlyK166-ATG10 [cytosol] [EntityWithAccessionedSequence:R-MMU-936391] Atg5 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ATG10:ATG12 binds ATG5
output	[Complex:R-MMU-5682657] ATG12:GlyK166-ATG10:ATG5 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5682010
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-1632852] Macroautophagy
(precedingEvent)	[Reaction:R-MMU-5683588] ATG10 transfers ATG12 from ATG10 to ATG5
(inferredTo)	[Reaction:R-HSA-5682010] ATG10:ATG12 binds ATG5

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