Reactome | PAK1 phosphorylates myosin phosphatase

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PAK1 phosphorylates myosin phosphatase Show undefined attributes

catalystActivity	[CatalystActivity:10040800] protein serine/threonine kinase activity of p-S144,T423-PAK1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10059160
displayName	PAK1 phosphorylates myosin phosphatase
eventOf	[Pathway:R-MMU-5627123] RHO GTPases activate PAKs - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5668947] PAK1 phosphorylates myosin phosphatase - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-MMU-419080] Myosin phosphatase [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PAK1 phosphorylates myosin phosphatase
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-MMU-5668948] p-T696-PPP1R12A-Myosin phosphatase [cytosol]
precedingEvent	[Reaction:R-MMU-2029454] Autophosphorylation of PAK1 - Mus musculus [Reaction:R-MMU-5627775] Autophosphorylation of PAK1,2,3 - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5668947
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-5627123] RHO GTPases activate PAKs
(inferredTo)	[Reaction:R-HSA-5668947] PAK1 phosphorylates myosin phosphatase

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