Reactome | SPRTN binds monoUb:K164-PCNA associated with POLH

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SPRTN binds monoUb:K164-PCNA associated with POLH Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10058333
displayName	SPRTN binds monoUb:K164-PCNA associated with POLH
eventOf	[Pathway:R-MMU-110320] Translesion Synthesis by POLH - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-5654985] SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH - Mus musculus
inferredFrom	[Reaction:R-HSA-5654986] SPRTN binds monoUb:K164-PCNA associated with POLH - Homo sapiens
input	[Complex:R-MMU-5654981] POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-5643744] SPRTN [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	SPRTN binds monoUb:K164-PCNA associated with POLH
output	[Complex:R-MMU-5654984] SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm]
precedingEvent	[Reaction:R-MMU-110319] Elongation by POLH - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5654986
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-110320] Translesion Synthesis by POLH
(precedingEvent)	[Reaction:R-MMU-5654985] SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH
(inferredTo)	[Reaction:R-HSA-5654986] SPRTN binds monoUb:K164-PCNA associated with POLH

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