Reactome | Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10058113
displayName	Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane]
hasComponent	[DefinedSet:R-MMU-5654262] Activated FGFR1:p-FRS [plasma membrane] [EntityWithAccessionedSequence:R-MMU-162573] phospho-p-Y542,Y580-PTPN11 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5654271] Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane] - Homo sapiens
isRequired	[Requirement:10081823] Requirement by 'Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane]'
maxDepth	10
name	Activated FGFR1:p-FRS:p-PTPN11
positivelyRegulates	[Requirement:10081823] Requirement by 'Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane]'
producedByEvent	[Reaction:R-MMU-5654587] Activated FGFR1:p-FRS phosphorylates PPTN11 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5654271
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(regulator)	[Requirement:10081823] Requirement by 'Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane]'
(output)	[Reaction:R-MMU-5654587] Activated FGFR1:p-FRS phosphorylates PPTN11
(inferredTo)	[Complex:R-HSA-5654271] Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane]

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