Reactome | TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-MMU-3371359] FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling - Mus musculus [Reaction:R-MMU-141156] TRAIL-mediated dimerization of procaspase-8 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9989948
displayName	TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-MMU-57031] Casp8 [cytosol] [Complex:R-MMU-5637464] TNFSF10:TNFRSF10A,B:FADD [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-5637468] TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane] - Homo sapiens
maxDepth	6
name	TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479)
producedByEvent	[Reaction:R-MMU-75146] TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-5637468
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-3371359] FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling [Reaction:R-MMU-141156] TRAIL-mediated dimerization of procaspase-8
(output)	[Reaction:R-MMU-75146] TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8
(inferredTo)	[Complex:R-HSA-5637468] TNFSF10:TNFRSF10A,B:FADD:CASP8(1-479) [plasma membrane]

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