Reactome | Egr2 activates Hoxa2 chromatin

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Egr2 activates Hoxa2 chromatin Show undefined attributes

authored	[InstanceEdit:5618010] May, Bruce, 2014-08-16 [InstanceEdit:6810137] Rezsohazy, Ren�, 2015-11-15
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:5619416] May, Bruce, 2014-08-22
dbId	5619428
displayName	Egr2 activates Hoxa2 chromatin
edited	[InstanceEdit:5618010] May, Bruce, 2014-08-16
followingEvent	[BlackBoxEvent:R-MMU-5619418] Hoxa2 gene is transcribed - Mus musculus
input	[EntityWithAccessionedSequence:R-MMU-977395] Egr2 [nucleoplasm] [Complex:R-MMU-6810134] Hoxa2 active chromatin [nucleoplasm] [Complex:R-MMU-216411] RNA polymerase II holoenzyme (generic) [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5619212] A regulatory module embedded in the coding region of Hoxa2 controls expression in rhombomere 2 [LiteratureReference:5619174] Differences in Krox20-dependent regulation of Hoxa2 and Hoxb2 during hindbrain development [LiteratureReference:5621516] The Hoxa2 enhancer 2 contains a critical Hoxa2 responsive regulatory element [LiteratureReference:5619162] Expression of Hoxa2 in rhombomere 4 is regulated by a conserved cross-regulatory mechanism dependent upon Hoxb1 [LiteratureReference:5619331] An ultraconserved Hox-Pbx responsive element resides in the coding sequence of Hoxa2 and is active in rhombomere 4
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Egr2 activates Hoxa2 chromatin
orthologousEvent	[BlackBoxEvent:R-HSA-5617484] EGR2 (KROX20) activates HOXA2 expression - Homo sapiens
output	[Complex:R-MMU-5619401] Egr2 at active Hoxa2 chromatin [nucleoplasm]
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5693642] Blasi, F, 2015-05-13
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-5619428
summation	[Summation:5621513] Hoxa2 expression in embryos is driven by Egr2 (Krox20) in rh...

Referrals

(precedingEvent)

[BlackBoxEvent:R-MMU-5619418] Hoxa2 gene is transcribed

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