Reactome | Hoxd4 gene is transcribed

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Hoxd4 gene is transcribed Show undefined attributes

authored	[InstanceEdit:5618010] May, Bruce, 2014-08-16 [InstanceEdit:6810137] Rezsohazy, Ren�, 2015-11-15
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:5619416] May, Bruce, 2014-08-22
dbId	5619421
displayName	Hoxd4 gene is transcribed
edited	[InstanceEdit:5618010] May, Bruce, 2014-08-16
followingEvent	[BlackBoxEvent:R-MMU-5619415] Hoxd4 mRNA is translated - Mus musculus
input	[EntityWithAccessionedSequence:R-MMU-5619403] Hoxd4 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5619264] RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid [LiteratureReference:5619453] Direct crossregulation between retinoic acid receptor {beta} and Hox genes during hindbrain segmentation [LiteratureReference:5619470] The role of a retinoic acid response element in establishing the anterior neural expression border of Hoxd4 transgenes [LiteratureReference:5619469] Murine hoxd4 expression in the CNS requires multiple elements including a retinoic acid response element [LiteratureReference:5619444] Characterization and retinoic acid responsiveness of the murine Hoxd4 transcription unit [LiteratureReference:5619472] Elements both 5' and 3' to the murine Hoxd4 gene establish anterior borders of expression in mesoderm and neurectoderm [LiteratureReference:5619446] Identification of a retinoic acid response element upstream of the murine Hox-4.2 gene [LiteratureReference:5621534] Interplay between chromatin and trans-acting factors regulating the Hoxd4 promoter during neural differentiation [LiteratureReference:5621528] Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-posterior axis [LiteratureReference:5689918] Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code [LiteratureReference:5689987] Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2 [LiteratureReference:5617910] Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hoxd4 gene is transcribed
orthologousEvent	[BlackBoxEvent:R-HSA-5617874] HOXD4 gene is transcribed - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-5619369] Hoxd4 mRNA [cytosol]
precedingEvent	[BlackBoxEvent:R-MMU-5619441] Retinoic acid activates Hoxd4 chromatin - Mus musculus
regulatedBy	[PositiveRegulation:R-MMU-5634084] Positive regulation by 'atRA:Rara,b:Rxra at active Hoxd4 chromatin [nucleoplasm]'
regulationReference	[RegulationReference:9641930] Positive regulation by 'atRA:Rara,b:Rxra at active Hoxd4 chromatin [nucleoplasm]' A genetic approach to the recruitment of PRC2 at the HoxD locus
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5693642] Blasi, F, 2015-05-13
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-5619421
summation	[Summation:5621688] The Hoxd4 gene is transcribed to yield mRNA (Featherstone et...

Referrals

(precedingEvent)

[BlackBoxEvent:R-MMU-5619415] Hoxd4 mRNA is translated

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