Reactome | Activated protein C is released from PROCR

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Activated protein C is released from PROCR Show undefined attributes

category	dissociation
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10055353
displayName	Activated protein C is released from PROCR
eventOf	[Pathway:R-MMU-9769739] Regulation of clotting cascade - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-5604929] Activated protein C binds Protein S - Mus musculus
inferredFrom	[Reaction:R-HSA-5603467] Activated protein C is released from PROCR - Homo sapiens
input	[Complex:R-MMU-5603469] PROCR:Activated protein C [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Activated protein C is released from PROCR
output	[Complex:R-MMU-141050] Activated protein C [extracellular region] [EntityWithAccessionedSequence:R-MMU-5591027] Procr [plasma membrane]
precedingEvent	[Reaction:R-MMU-141040] Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5603467
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9769739] Regulation of clotting cascade
(precedingEvent)	[Reaction:R-MMU-5604929] Activated protein C binds Protein S
(inferredTo)	[Reaction:R-HSA-5603467] Activated protein C is released from PROCR

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