Reactome | Transcriptional regulation by small RNAs

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Transcriptional regulation by small RNAs Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10101151
displayName	Transcriptional regulation by small RNAs
eventOf	[Pathway:R-MMU-211000] Gene Silencing by RNA - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:447604] regulation of miRNA-mediated gene silencing
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-5578712] Importin-8 binds AGO2:miRNA - Mus musculus [Reaction:R-MMU-5578744] Importin-8 imports AGO2:miRNA into the nucleus - Mus musculus [Reaction:R-MMU-5578965] TNRC6A binds AGO2:miRNA - Mus musculus [BlackBoxEvent:R-MMU-5578966] TNRC6A:AGO2:miRNA is transported into the nucleus - Mus musculus
inferredFrom	[Pathway:R-HSA-5578749] Transcriptional regulation by small RNAs - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Transcriptional regulation by small RNAs
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-5578749
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-211000] Gene Silencing by RNA
(inferredTo)	[Pathway:R-HSA-5578749] Transcriptional regulation by small RNAs

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