Reactome | Expression of Nr1d1 (Rev-erba)

Schema > BlackBoxEvent > Entries

Expression of Nr1d1 (Rev-erba) Show undefined attributes

authored	[InstanceEdit:517836] May, B, 2010-02-20
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:549380] May, B, 2010-03-21
dbId	549505
deleted	[Deleted:9032447] Deletion of instance: 1368110 [Deleted:9032444] Deletion of instance: 1368092 [Deleted:9032440] Deletion of instance: 5334727
displayName	Expression of Nr1d1 (Rev-erba)
edited	[InstanceEdit:517836] May, B, 2010-02-20
followingEvent	[Reaction:R-MMU-5667077] Nr1d1 (Rev-erba) binds heme, the Elovl3 gene, and recruits corepressors - Mus musculus
input	[EntityWithAccessionedSequence:R-MMU-5663171] Nr1d1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:549365] The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker [LiteratureReference:879761] The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator
maxDepth	1
modified	[InstanceEdit:9939539] May, Bruce, 2025-02-28
name	Expression of Nr1d1 (Rev-erba)
orthologousEvent	[BlackBoxEvent:R-HSA-549475] Expression of NR1D1 (REV-ERBA) - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-508732] Nr1d1 [nucleoplasm]
regulatedBy	[PositiveRegulation:R-MMU-549591] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Nr1d1 gene [nucleoplasm]' [PositiveRegulation:R-MMU-5663302] Positive regulation by 'Rora:Coactivator:Nr1d1 gene [nucleoplasm]' [NegativeGeneExpressionRegulation:R-MMU-5667094] Negative gene expression regulation by 'Nr1d1:heme:Corepressors:Nr1d1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642312] Positive regulation by 'p-Bmal1:p-Clock,Npas2:Nr1d1 gene [nucleoplasm]' The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker [RegulationReference:9642445] Positive regulation by 'Rora:Coactivator:Nr1d1 gene [nucleoplasm]' Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:879756] Albrecht, Urs, 2010-06-23 [InstanceEdit:879786] Delaunay, F, 2010-06-23 [InstanceEdit:879790] Hirota, T, 2010-06-23 [InstanceEdit:879726] Kay, SA, 2010-06-23
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-549505
summation	[Summation:549506] The Nr1d1 (Rev-erba) gene is transcribed to yield mRNA and t...
updateTrackers	[UpdateTracker:9788953] Update Tracker - [BlackBoxEvent:549505] Expression of Nr1d1 (Rev-erba) - v39:[removeCatalystActivity] [UpdateTracker:9785111] Update Tracker - [BlackBoxEvent:549505] Expression of Nr1d1 (Rev-erba) - v52:[addInput, add_removeRegulator] [UpdateTracker:9787211] Update Tracker - [BlackBoxEvent:549505] Expression of Nr1d1 (Rev-erba) - v46:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9788953] Update Tracker - [BlackBoxEvent:549505] Expression of Nr1d1 (Rev-erba) - v39:[removeCatalystActivity] [UpdateTracker:9785111] Update Tracker - [BlackBoxEvent:549505] Expression of Nr1d1 (Rev-erba) - v52:[addInput, add_removeRegulator] [UpdateTracker:9787211] Update Tracker - [BlackBoxEvent:549505] Expression of Nr1d1 (Rev-erba) - v46:[modifyText]
(replacementInstances)	[Deleted:9032440] Deletion of instance: 5334727 [Deleted:9032447] Deletion of instance: 1368110 [Deleted:9032444] Deletion of instance: 1368092
(precedingEvent)	[Reaction:R-MMU-5667077] Nr1d1 (Rev-erba) binds heme, the Elovl3 gene, and recruits corepressors

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