Reactome | OCT2 mediates tubular uptake of organic cations in the kidney

Schema > Reaction > Entries

OCT2 mediates tubular uptake of organic cations in the kidney Show undefined attributes

catalystActivity	[CatalystActivity:10020315] transmembrane transporter activity of SLC22A1,SLC22A2 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10020317
displayName	OCT2 mediates tubular uptake of organic cations in the kidney
eventOf	[Pathway:R-MMU-549127] SLC-mediated transport of organic cations - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-549279] OCT2 mediates tubular uptake of organic cations in the kidney - Homo sapiens
input	[DefinedSet:R-ALL-549237] OCT2 substrates [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	OCT2 mediates tubular uptake of organic cations in the kidney
output	[DefinedSet:R-ALL-549266] OCT2 substrates [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-549279
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-549127] SLC-mediated transport of organic cations
(inferredTo)	[Reaction:R-HSA-549279] OCT2 mediates tubular uptake of organic cations in the kidney

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