Reactome | Hydrolysis of GTP and dissociation of 28S and 39S subunits

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Hydrolysis of GTP and dissociation of 28S and 39S subunits Show undefined attributes

catalystActivity	[CatalystActivity:10054995] GTPase activity of 55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane]
category	transition
compartment	[Compartment:5460] mitochondrial matrix [Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10054997
displayName	Hydrolysis of GTP and dissociation of 28S and 39S subunits
eventOf	[Pathway:R-MMU-5419276] Mitochondrial translation termination - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5419273] Hydrolysis of GTP and dissociation of 28S and 39S subunits - Homo sapiens
input	[Complex:R-MMU-5419282] 55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Hydrolysis of GTP and dissociation of 28S and 39S subunits
output	[Complex:R-MMU-5368239] 28S ribosomal subunit [mitochondrial inner membrane] [Complex:R-MMU-5368233] 39S ribosomal subunit [mitochondrial inner membrane] [Complex:R-MMU-5419266] GFM2:GDP [mitochondrial matrix] [EntityWithAccessionedSequence:R-MMU-5419265] Mrrf [mitochondrial matrix] [SimpleEntity:R-ALL-113548] Pi [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5419273
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-5419276] Mitochondrial translation termination
(inferredTo)	[Reaction:R-HSA-5419273] Hydrolysis of GTP and dissociation of 28S and 39S subunits

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