Reactome | WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6

Schema > BlackBoxEvent > Entries

WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 Show undefined attributes

category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:171062] early endosome membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10054571
displayName	WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6
eventOf	[Pathway:R-MMU-4641262] Disassembly of the destruction complex and recruitment of AXIN to the membrane - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-5368596] WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 - Homo sapiens
input	[Complex:R-MMU-5368521] WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6
output	[Complex:R-MMU-5368519] WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-5368596
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-4641262] Disassembly of the destruction complex and recruitment of AXIN to the membrane
(inferredTo)	[BlackBoxEvent:R-HSA-5368596] WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6

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