Reactome | PTK2B is phosphorylated

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10020176
displayName	PTK2B is phosphorylated
eventOf	[Pathway:R-MMU-9020558] Interleukin-2 signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-508451] PTK2B is phosphorylated - Homo sapiens
input	[Complex:R-MMU-508512] JAK3:PYK2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PTK2B is phosphorylated Pyk2 is activated following IL2 stimulation
output	[Complex:R-MMU-508510] JAK3:p-PYK2 [cytosol]
precedingEvent	[Reaction:R-MMU-508513] PTK2B binds JAK3 - Mus musculus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-508451
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-9020558] Interleukin-2 signaling
(inferredTo)	[BlackBoxEvent:R-HSA-508451] PTK2B is phosphorylated

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