Reactome | SUMOylation of immune response proteins

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SUMOylation of immune response proteins Show undefined attributes

compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10101085
displayName	SUMOylation of immune response proteins
eventOf	[Pathway:R-MMU-3108232] SUMO E3 ligases SUMOylate target proteins - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-4755478] TOPORS SUMOylates IKBKE with SUMO1 - Mus musculus [Reaction:R-MMU-4755411] PIAS4 SUMOylates IKBKG with SUMO1 - Mus musculus [Reaction:R-MMU-4656914] SUMOylation of NFKBIA with SUMO1 - Mus musculus [Reaction:R-MMU-4755479] SUMOylation of NFKB2 with SUMO1 - Mus musculus [Reaction:R-MMU-4755536] PIAS3 SUMOylates RELA with SUMO3 - Mus musculus
inferredFrom	[Pathway:R-HSA-4755510] SUMOylation of immune response proteins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SUMOylation of immune response proteins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-4755510
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-3108232] SUMO E3 ligases SUMOylate target proteins
(hasEncapsulatedEvent)	[Pathway:R-MMU-9833482] PKR-mediated signaling
(inferredTo)	[Pathway:R-HSA-4755510] SUMOylation of immune response proteins

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