Reactome | Pias1,2-2 Sumoylate Pparg with Sumo1

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Pias1,2-2 Sumoylate Pparg with Sumo1 Show undefined attributes

authored	[InstanceEdit:4686132] May, B, 2013-10-11
catalystActivity	[CatalystActivity:4717460] SUMO transferase activity of Pias1,2-2 [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643475] SUMO transferase activity of Pias1,2-2 [nucleoplasm] Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:4717498] May, B, 2013-10-18
dbId	4717507
displayName	Pias1,2-2 Sumoylate Pparg with Sumo1
edited	[InstanceEdit:4686132] May, B, 2013-10-11
input	[EntityWithAccessionedSequence:R-MMU-4717453] Pparg [nucleoplasm] 2 × [Complex:R-MMU-3232135] Sumo1:C93-Ube2i [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:4717496] Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification [LiteratureReference:4717449] Control of peroxisome proliferator-activated receptor gamma2 stability and activity by SUMOylation [LiteratureReference:4717478] The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain [LiteratureReference:4717501] Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines [LiteratureReference:4717447] A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Pias1,2-2 Sumoylate Pparg with Sumo1
orthologousEvent	[Reaction:R-HSA-4717461] PIAS1,2-2 SUMOylate PPARG with SUMO1 - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-4717458] monoSumo1-K107,K395-Pparg [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-MMU-912483] Ube2i [nucleoplasm]
releaseDate	2018-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608076] Niskanen, Einari, 2018-05-09 [InstanceEdit:9615865] Niskanen, Einari, 2018-08-08
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-4717507
summation	[Summation:4717457] Pias1,2-1 sumoylate Pparg with Sumo1 at lysine-107 and lysin...
updateTrackers	[UpdateTracker:9774889] Update Tracker - [Reaction:4717507] Pias1,2-2 Sumoylate Pparg with Sumo1 - v80:[add_removeOutput]

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[UpdateTracker:9774889] Update Tracker - [Reaction:4717507] Pias1,2-2 Sumoylate Pparg with Sumo1 - v80:[add_removeOutput]