Reactome | IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-508246] IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] - Mus musculus [Complex:R-MMU-912523] IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10019207
displayName	IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane]
hasComponent	[Complex:R-MMU-452119] IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-162568] phospho-Shc1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-453099] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane] - Homo sapiens
maxDepth	4
memberOf	[DefinedSet:R-MMU-912534] Interleukin receptor complexes with activated SHC1 [plasma membrane] - Mus musculus
name	IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC
producedByEvent	[Reaction:R-MMU-452100] SHC1 bound to IL2 receptor is phosphorylated - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-453099
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-MMU-508246] IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane] [Complex:R-MMU-912523] IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane]
(output)	[Reaction:R-MMU-452100] SHC1 bound to IL2 receptor is phosphorylated
(hasMember)	[DefinedSet:R-MMU-912534] Interleukin receptor complexes with activated SHC1 [plasma membrane]
(inferredTo)	[Complex:R-HSA-453099] IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHC [plasma membrane]

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