Reactome | AUF1:mRNA complex is degraded

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AUF1:mRNA complex is degraded Show undefined attributes

catalystActivity	[CatalystActivity:9985423] endopeptidase activity of 26S proteasome [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10018845
displayName	AUF1:mRNA complex is degraded
eventOf	[Pathway:R-MMU-450408] AUF1 (hnRNP D0) binds and destabilizes mRNA - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-450466] AUF1:mRNA complex is degraded - Homo sapiens
input	[Complex:R-MMU-450458] Ubiquitinated AUF1 Tetramer: Destabilized mRNA Complex [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AUF1:mRNA complex is degraded
output	12 × [DefinedSet:R-MMU-113595] Ub [cytosol]
precedingEvent	[BlackBoxEvent:R-MMU-450580] AUF1 (hnRNP D0) is ubiquitinylated - Mus musculus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-450466
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-450408] AUF1 (hnRNP D0) binds and destabilizes mRNA
(inferredTo)	[BlackBoxEvent:R-HSA-450466] AUF1:mRNA complex is degraded

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