Reactome | TAK1 is activated within the TAK1 complex

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TAK1 is activated within the TAK1 complex Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10018608
displayName	TAK1 is activated within the TAK1 complex
eventOf	[Pathway:R-MMU-9020702] Interleukin-1 signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-450187] TAK1 is activated within the TAK1 complex - Homo sapiens
input	[Complex:R-MMU-450185] hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	TAK1 is activated within the TAK1 complex
output	[Complex:R-MMU-450186] hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol]
precedingEvent	[Reaction:R-MMU-688985] K63 polyubiquitinated RIP2 associates with the TAK1 complex - Mus musculus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-450187
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9020702] Interleukin-1 signaling
(inferredTo)	[BlackBoxEvent:R-HSA-450187] TAK1 is activated within the TAK1 complex

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