Reactome | DOLK phosphorylates DCHOL to DOLP

Schema > Reaction > Entries

DOLK phosphorylates DCHOL to DOLP Show undefined attributes

catalystActivity	[CatalystActivity:10017792] dolichol kinase activity of DOLK [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10017794
displayName	DOLK phosphorylates DCHOL to DOLP
eventOf	[Pathway:R-MMU-446199] Synthesis of dolichyl-phosphate - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-446191] Addition of N-acetyl-D-glucosamine to Dolichyl phosphate - Mus musculus
inferredFrom	[Reaction:R-HSA-446195] DOLK phosphorylates DCHOL to DOLP - Homo sapiens
input	[SimpleEntity:R-ALL-110614] CTP [cytosol] [SimpleEntity:R-ALL-449221] DCHOL [cytoplasmic side of endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	DOLK phosphorylates DCHOL to DOLP a di-trans,poly-cis-dolichol + CTP => CDP + a di-trans,poly-cis-dolichyl phosphate + H(+)
output	[SimpleEntity:R-ALL-110094] CDP [cytosol] [SimpleEntity:R-ALL-449299] DOLP [cytoplasmic side of endoplasmic reticulum membrane] [SimpleEntity:R-ALL-70106] H+ [cytosol]
precedingEvent	[Reaction:R-MMU-9937340] DHRSX reduces dolichal to dolichol - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-446195
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-446199] Synthesis of dolichyl-phosphate
(precedingEvent)	[Reaction:R-MMU-446191] Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
(inferredTo)	[Reaction:R-HSA-446195] DOLK phosphorylates DCHOL to DOLP

Cite Us!