Reactome | Activation of Phospholipase C beta1 by G(q)alpha:GTP

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Activation of Phospholipase C beta1 by G(q)alpha:GTP Show undefined attributes

authored	[InstanceEdit:445855] May, B, 2009-11-06
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:445863] May, B, 2009-11-06
dbId	445860
displayName	Activation of Phospholipase C beta1 by G(q)alpha:GTP
edited	[InstanceEdit:445855] May, B, 2009-11-06
input	[EntityWithAccessionedSequence:R-MMU-445858] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 [plasma membrane] [Complex:R-MMU-445852] G-alpha(q):GTP [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:416365] Galphaq binds two effectors separately in cells: evidence for predetermined signaling pathways [LiteratureReference:445859] A self-scaffolding model for G protein signaling [LiteratureReference:383358] Stable association between G alpha(q) and phospholipase C beta 1 in living cells [LiteratureReference:445865] Selective interaction of the C2 domains of phospholipase C-beta1 and -beta2 with activated Galphaq subunits: an alternative function for C2-signaling modules [LiteratureReference:445853] Determination of the affinities between heterotrimeric G protein subunits and their phospholipase C-beta effectors
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activation of Phospholipase C beta1 by G(q)alpha:GTP
orthologousEvent	[Reaction:R-HSA-400023] Gq alpha activates Phospholipase C beta - Homo sapiens
output	[Complex:R-MMU-445857] Phospholipase C Beta1:G(q)alpha Complex [plasma membrane]
releaseDate	2009-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:445855] May, B, 2009-11-06
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-445860
summation	[Summation:445864] The G(q)alpha subunit bound to GTP interacts with Phospholip...

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