Reactome | GpIb-IX-V:Collagen type I fibril:vWF [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-429544] GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane] - Mus musculus [Complex:R-MMU-429532] GP1b-IX-V complex:activated thrombin (factor IIa) [plasma membrane] - Mus musculus
consumedByEvent	[BlackBoxEvent:R-MMU-443418] GP1b signaling involves c-Src - Mus musculus [Reaction:R-MMU-430076] GP1b-IX-V binds 14-3-3-zeta - Mus musculus [Reaction:R-MMU-429529] Thrombin binding to GP1b:IX:V - Mus musculus [Reaction:R-MMU-430096] GP1b-IX-V binds filamin - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10016115
displayName	GpIb-IX-V:Collagen type I fibril:vWF [plasma membrane]
hasComponent	[Complex:R-MMU-114596] Collagen type I fibril:vWF [extracellular region] [Complex:R-MMU-114668] GPIb-IX-V [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-435464] GpIb-IX-V:Collagen type I fibril:vWF [plasma membrane] - Homo sapiens
maxDepth	6
name	GpIb-IX-V:Collagen type I fibril:vWF
producedByEvent	[Reaction:R-MMU-430073] GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-435464
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-429529] Thrombin binding to GP1b:IX:V [BlackBoxEvent:R-MMU-443418] GP1b signaling involves c-Src [Reaction:R-MMU-430096] GP1b-IX-V binds filamin [Reaction:R-MMU-430076] GP1b-IX-V binds 14-3-3-zeta
(hasComponent)	[Complex:R-MMU-429532] GP1b-IX-V complex:activated thrombin (factor IIa) [plasma membrane] [Complex:R-MMU-430104] GPIb-IX-V:vWF:filamin-A [plasma membrane] [Complex:R-MMU-429544] GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane]
(output)	[Reaction:R-MMU-430073] GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress
(inferredTo)	[Complex:R-HSA-435464] GpIb-IX-V:Collagen type I fibril:vWF [plasma membrane]