Reactome | SLC26A3,6 exchange Cl- for HCO3-

Schema > Reaction > Entries

SLC26A3,6 exchange Cl- for HCO3- Show undefined attributes

catalystActivity	[CatalystActivity:10015679] solute:inorganic anion antiporter activity of SLC26A3,6 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10015681
displayName	SLC26A3,6 exchange Cl- for HCO3-
eventOf	[Pathway:R-MMU-427601] Inorganic anion exchange by SLC26 transporters - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-425577] Na+-driven Cl-/HCO3- exchanger transport - Mus musculus
inferredFrom	[Reaction:R-HSA-427666] SLC26A3,6 exchange Cl- for HCO3- - Homo sapiens
input	[SimpleEntity:R-ALL-188972] Cl- [extracellular region] [SimpleEntity:R-ALL-111627] HCO3- [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC26A3,6 exchange Cl- for HCO3- Group 2 - Cl-/HCO3- exchanger transport
output	[SimpleEntity:R-ALL-352022] Cl- [cytosol] [SimpleEntity:R-ALL-425425] HCO3- [extracellular region]
precedingEvent	[Reaction:R-MMU-425577] Na+-driven Cl-/HCO3- exchanger transport - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-427666
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-427601] Inorganic anion exchange by SLC26 transporters
(precedingEvent)	[Reaction:R-MMU-425577] Na+-driven Cl-/HCO3- exchanger transport
(inferredTo)	[Reaction:R-HSA-427666] SLC26A3,6 exchange Cl- for HCO3-

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