Reactome | ADP signalling through P2Y purinoceptor 1

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ADP signalling through P2Y purinoceptor 1 Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100205
displayName	ADP signalling through P2Y purinoceptor 1
eventOf	[Pathway:R-MMU-392518] Signal amplification - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20684] platelet activation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-417908] P2RY1 binds ADP - Mus musculus [Reaction:R-MMU-418576] Dissociation of the P2Y purinoceptor 1:Gq complex - Mus musculus [BlackBoxEvent:R-MMU-418662] Src activation following P2Y purinoceptor activation - Mus musculus [BlackBoxEvent:R-MMU-428941] P2Y purinoceptor 1 activates MAP kinase p38 alpha - Mus musculus [Reaction:R-MMU-428961] Phosphorylation of cPLA2 by MAPK p38 alpha - Mus musculus
inferredFrom	[Pathway:R-HSA-418592] ADP signalling through P2Y purinoceptor 1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	ADP signalling through P2Y purinoceptor 1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-418592
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-392518] Signal amplification
(inferredTo)	[Pathway:R-HSA-418592] ADP signalling through P2Y purinoceptor 1

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