Reactome | Glutamate binding, activation of AMPA receptors and synaptic plasticity

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Glutamate binding, activation of AMPA receptors and synaptic plasticity Show undefined attributes

compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100173
displayName	Glutamate binding, activation of AMPA receptors and synaptic plasticity
eventOf	[Pathway:R-MMU-112314] Neurotransmitter receptors and postsynaptic signal transmission - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:645] chemical synaptic transmission
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-MMU-399719] Trafficking of AMPA receptors - Mus musculus [Pathway:R-MMU-399710] Activation of AMPA receptors - Mus musculus
inferredFrom	[Pathway:R-HSA-399721] Glutamate binding, activation of AMPA receptors and synaptic plasticity - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Glutamate binding, activation of AMPA receptors and synaptic plasticity
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-399721
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-112314] Neurotransmitter receptors and postsynaptic signal transmission
(hasEncapsulatedEvent)	[Pathway:R-MMU-442755] Activation of NMDA receptors and postsynaptic events
(inferredTo)	[Pathway:R-HSA-399721] Glutamate binding, activation of AMPA receptors and synaptic plasticity

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