Reactome | Activation of CDC42 by intersectin-1

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Activation of CDC42 by intersectin-1 Show undefined attributes

authored	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
catalystActivity	[CatalystActivity:8939810] guanyl-nucleotide exchange factor activity of Unknown GEF [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:3928638] Garapati, P V, 2013-07-22
dbId	3928643
displayName	Activation of CDC42 by intersectin-1
edited	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
input	[Complex:R-MMU-3928558] Cdc42:GDP [cytosol] [SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-MMU-3928547] p-EphB2:intersectin-1:N-Wasp [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3928082] EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activation of CDC42 by intersectin-1
orthologousEvent	[Reaction:R-HSA-3928632] ITSN1 exchanges GTP for GDP on CDC42, activating it - Homo sapiens
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-MMU-3928516] p-EphB2:intersectin-1:N-Wasp:Cdc42:GTP [plasma membrane]
releaseDate	2014-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5490284] Ip, Nancy Y, 2014-05-19
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-3928643
summation	[Summation:3928280] Activated intersectin 1 (ITSN1) activates CDC42 by exchangin...
updateTrackers	[UpdateTracker:9782472] Update Tracker - [Reaction:3928643] Activation of CDC42 by intersectin-1 - v59:[add_removeCatalystActivity]

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(updatedInstance)

[UpdateTracker:9782472] Update Tracker - [Reaction:3928643] Activation of CDC42 by intersectin-1 - v59:[add_removeCatalystActivity]

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