Reactome | Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10013481] guanyl-nucleotide exchange factor activity of Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10013478
displayName	Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane]
hasComponent	[Complex:R-MMU-391842] NCAM1 complexed with pFyn-Y420 [plasma membrane] [Complex:R-MMU-392044] pFAK:Grb2:Sos [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-392045] Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] - Homo sapiens
maxDepth	6
memberOf	[DefinedSet:R-MMU-5672601] RAS GEFs [plasma membrane] - Mus musculus
name	Grb2:Sos:pFAK bound to NCAM1:pFyn
producedByEvent	[Reaction:R-MMU-392053] SOS binds Grb2 bound to pFAK:NCAM1 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-392045
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10013481] guanyl-nucleotide exchange factor activity of Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane]
(output)	[Reaction:R-MMU-392053] SOS binds Grb2 bound to pFAK:NCAM1
(hasMember)	[DefinedSet:R-MMU-5672601] RAS GEFs [plasma membrane]
(inferredTo)	[Complex:R-HSA-392045] Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane]

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