Reactome | EP2 and EP4 receptors can bind PGE2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10013419
displayName	EP2 and EP4 receptors can bind PGE2
eventOf	[Pathway:R-MMU-391908] Prostanoid ligand receptors - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-391940] EP2 and EP4 receptors can bind PGE2 - Homo sapiens
input	[SimpleEntity:R-ALL-391930] PGE2 [extracellular region] [DefinedSet:R-MMU-391921] PTGER2,PTGER4 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	EP2 and EP4 receptors can bind PGE2
output	[Complex:R-MMU-416880] PTGER2,PTGER4:PGE2 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-391940
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-391908] Prostanoid ligand receptors
(inferredTo)	[Reaction:R-HSA-391940] EP2 and EP4 receptors can bind PGE2

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