Reactome | Grb7 binds to the active PDGF receptor

Schema > Reaction > Entries

Grb7 binds to the active PDGF receptor Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10012356
displayName	Grb7 binds to the active PDGF receptor
eventOf	[Pathway:R-MMU-186763] Downstream signal transduction - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-382055] Grb7 binds to the active PDGF receptor - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-204819] Grb7 [cytosol] [Complex:R-MMU-186811] PDGF:Phospho-PDGF receptor dimer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Grb7 binds to the active PDGF receptor
output	[Complex:R-MMU-381956] PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane]
precedingEvent	[Reaction:R-MMU-389083] Autophosphorylation of PDGF alpha receptors - Mus musculus [Reaction:R-MMU-389086] Autophosphorylation of PDGF alpha/beta receptors - Mus musculus [Reaction:R-MMU-186786] Autophosphorylation of PDGF beta receptors - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-382055
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-186763] Downstream signal transduction
(inferredTo)	[Reaction:R-HSA-382055] Grb7 binds to the active PDGF receptor