Reactome | MAOA:FAD deaminates 3MT to HVA

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MAOA:FAD deaminates 3MT to HVA Show undefined attributes

catalystActivity	[CatalystActivity:9994017] primary methylamine oxidase activity of MAOA:FAD [mitochondrial outer membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10011124
displayName	MAOA:FAD deaminates 3MT to HVA
eventOf	[Pathway:R-MMU-379397] Enzymatic degradation of dopamine by COMT - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-379395] MAOA:FAD deaminates 3MT to HVA - Homo sapiens
input	[SimpleEntity:R-ALL-8954997] 3MT [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MAOA:FAD deaminates 3MT to HVA Oxidation of 3-Methoxytyramine to homovanillic acid
output	[SimpleEntity:R-ALL-29408] H2O2 [cytosol] [SimpleEntity:R-ALL-9677992] HVA [cytosol] [SimpleEntity:R-ALL-29382] NH3 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-379395
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-379397] Enzymatic degradation of dopamine by COMT
(inferredTo)	[Reaction:R-HSA-379395] MAOA:FAD deaminates 3MT to HVA

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