Reactome | DISC:procaspase-8 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-3465352] DISC:procaspase-8:FLIP(S) [plasma membrane] - Mus musculus [Complex:R-MMU-3371381] DISC:procaspase-8:FLIP(L) [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-5675456] FLIP(L) and procaspase-8 form heterodimer - Mus musculus [Reaction:R-MMU-3465429] FLIP(S) and procaspase-8 form heterodimer - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10049049
displayName	DISC:procaspase-8 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-MMU-57031] Casp8 [cytosol] [DefinedSet:R-MMU-2671814] DISC [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-3465443] DISC:procaspase-8 [plasma membrane] - Homo sapiens
maxDepth	7
name	DISC:procaspase-8
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-3465443
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-5675456] FLIP(L) and procaspase-8 form heterodimer [Reaction:R-MMU-3465429] FLIP(S) and procaspase-8 form heterodimer
(hasComponent)	[Complex:R-MMU-3371381] DISC:procaspase-8:FLIP(L) [plasma membrane] [Complex:R-MMU-3465352] DISC:procaspase-8:FLIP(S) [plasma membrane]
(inferredTo)	[Complex:R-HSA-3465443] DISC:procaspase-8 [plasma membrane]