Reactome | GPX7,8 catalyze peroxidation of P4HB (PDI)

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GPX7,8 catalyze peroxidation of P4HB (PDI) Show undefined attributes

catalystActivity	[CatalystActivity:10048799] peroxidase activity of ERO1L:GPX7,8 [endoplasmic reticulum lumen]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10048801
displayName	GPX7,8 catalyze peroxidation of P4HB (PDI)
eventOf	[Pathway:R-MMU-3299685] Detoxification of Reactive Oxygen Species - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3341296] GPX7,8 catalyze peroxidation of P4HB (PDI) - Homo sapiens
input	[SimpleEntity:R-ALL-3341383] H2O2 [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:R-MMU-174692] P4hb [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	GPX7,8 catalyze peroxidation of P4HB (PDI)
output	2 × [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:R-MMU-3341287] P4hb [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-3341296
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-3299685] Detoxification of Reactive Oxygen Species
(inferredTo)	[Reaction:R-HSA-3341296] GPX7,8 catalyze peroxidation of P4HB (PDI)

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