Reactome | Cohesin Loading onto Chromatin

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100933
displayName	Cohesin Loading onto Chromatin
eventOf	[Pathway:R-MMU-68884] Mitotic Telophase/Cytokinesis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-2468040] Cohesin binds PDS5 and WAPAL - Mus musculus [Reaction:R-MMU-2470935] Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 - Mus musculus
inferredFrom	[Pathway:R-HSA-2470946] Cohesin Loading onto Chromatin - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Cohesin Loading onto Chromatin
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-2470946
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-68884] Mitotic Telophase/Cytokinesis
(inferredTo)	[Pathway:R-HSA-2470946] Cohesin Loading onto Chromatin

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