Reactome | LRAT esterifies RBP1:atROL and FACYLs to atREs

Schema > Reaction > Entries

LRAT esterifies RBP1:atROL and FACYLs to atREs Show undefined attributes

catalystActivity	[CatalystActivity:10044641] O-palmitoyltransferase activity of LRAT [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane [Compartment:13977] lipid droplet [Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10044958
displayName	LRAT esterifies RBP1:atROL and FACYLs to atREs
eventOf	[Pathway:R-MMU-2453902] The canonical retinoid cycle in rods (twilight vision) - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-2453833] RPE65 isomero-hydrolyses atREs to 11cROL - Mus musculus
inferredFrom	[Reaction:R-HSA-2453855] LRAT esterifies RBP1:atROL and FACYLs to atREs - Homo sapiens
input	[Complex:R-MMU-2864101] RBP1:atROL [cytosol] [SimpleEntity:R-ALL-9982900] RCOO- [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	LRAT esterifies RBP1:atROL and FACYLs to atREs LRAT esterifies all-trans-retinol in RPE
output	[SimpleEntity:R-ALL-9982476] atRE [lipid droplet] [EntityWithAccessionedSequence:R-MMU-74841] RBP1 [cytosol]
precedingEvent	[Reaction:R-MMU-74843] atROL binds RBP1 to form RBP1:atROL - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2453855
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2453902] The canonical retinoid cycle in rods (twilight vision)
(precedingEvent)	[Reaction:R-MMU-2453833] RPE65 isomero-hydrolyses atREs to 11cROL
(inferredTo)	[Reaction:R-HSA-2453855] LRAT esterifies RBP1:atROL and FACYLs to atREs

Cite Us!