Reactome | p-Y1161,1165,1166-IGF1R [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-2404189] IGF1,2:p-3Y-IGF1R [plasma membrane] - Mus musculus [Complex:R-MMU-9634580] ESTG:ESR1:p-3Y-IGF1R:SHC1 [plasma membrane] - Mus musculus
consumedByEvent	[BlackBoxEvent:R-MMU-9634584] Estrogen receptor binds IGF1R and SHC1 in response to estrogen - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10044661
displayName	p-Y1161,1165,1166-IGF1R [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-MMU-2404169] IGF1R(31-736) [plasma membrane] 2 × [EntityWithAccessionedSequence:R-MMU-2404172] phospho-p-Y1161,Y1165,Y1166-IGF1R(741-1367) [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-2404188] p-Y1161,1165,1166-IGF1R [plasma membrane] - Homo sapiens
maxDepth	2
name	p-Y1161,1165,1166-IGF1R
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-2404188
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-MMU-9634584] Estrogen receptor binds IGF1R and SHC1 in response to estrogen
(hasComponent)	[Complex:R-MMU-9634580] ESTG:ESR1:p-3Y-IGF1R:SHC1 [plasma membrane] [Complex:R-MMU-2404189] IGF1,2:p-3Y-IGF1R [plasma membrane]
(activeUnit)	[CatalystActivity:10044679] protein tyrosine kinase activity of IGF1,2:p-3Y-IGF1R:SHC1 [plasma membrane] [CatalystActivity:10044930] protein tyrosine kinase activity of IGF1,2:p-IGF1R:IRS1,2,4 [plasma membrane]
(inferredTo)	[Complex:R-HSA-2404188] p-Y1161,1165,1166-IGF1R [plasma membrane]