Reactome | VTN binds Plasminogen activator inhibitor- 1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10044520
displayName	VTN binds Plasminogen activator inhibitor- 1
eventOf	[Pathway:R-MMU-3000178] ECM proteoglycans - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2396079] VTN binds Plasminogen activator inhibitor- 1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-158797] Serpine1 [extracellular region] [EntityWithAccessionedSequence:R-MMU-215971] Vtn [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	VTN binds Plasminogen activator inhibitor- 1 VTN binds SERPINE1
output	[Complex:R-MMU-2466242] Vitronectin:Plasminogen activator inhibitor 1 [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2396079
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-3000178] ECM proteoglycans
(inferredTo)	[Reaction:R-HSA-2396079] VTN binds Plasminogen activator inhibitor- 1

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