Reactome | Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP

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Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP Show undefined attributes

catalystActivity	[CatalystActivity:10044354] ADP-ribose diphosphatase activity of NUDT9 [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10044356
displayName	Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP
eventOf	[Pathway:R-MMU-2393930] Phosphate bond hydrolysis by NUDT proteins - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2393954] Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP - Homo sapiens
input	[SimpleEntity:R-ALL-2393945] ADP-Rib [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP ADP-D-ribose + H2O => D-ribose 5-phosphate + AMP + 2 H(+)
output	[SimpleEntity:R-ALL-159448] AMP [mitochondrial matrix] 2 × [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-2393950] R5P [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2393954
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2393930] Phosphate bond hydrolysis by NUDT proteins
(inferredTo)	[Reaction:R-HSA-2393954] Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP

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