Reactome | PGH2 is isomerised to PGD2 by PTGDS

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PGH2 is isomerised to PGD2 by PTGDS Show undefined attributes

catalystActivity	[CatalystActivity:10042632] prostaglandin-D synthase activity of PTGDS [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10042634
displayName	PGH2 is isomerised to PGD2 by PTGDS
eventOf	[Pathway:R-MMU-2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX) - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2161620] PGH2 is isomerised to PGD2 by PTGDS - Homo sapiens
input	[SimpleEntity:R-ALL-30138] PGH2 [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	PGH2 is isomerised to PGD2 by PTGDS prostaglandin H2 => prostaglandin D2?
output	[SimpleEntity:R-ALL-2161634] PGD2 [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-MMU-140359] PGG2 is reduced to PGH2 by PTGS1 - Mus musculus [Reaction:R-MMU-2309773] PGG2 is reduced to PGH2 by PTGS2 - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-2161620
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2162123] Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
(inferredTo)	[Reaction:R-HSA-2161620] PGH2 is isomerised to PGD2 by PTGDS

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