Reactome | Cell surface interactions at the vascular wall

Schema > Pathway > Entries

Cell surface interactions at the vascular wall Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10099089
displayName	Cell surface interactions at the vascular wall
eventOf	[TopLevelPathway:R-MMU-109582] Hemostasis - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:160572] leukocyte migration
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-202727] Integrin alphaMbeta2 (MAC1) binds JAM3 - Mus musculus [Reaction:R-MMU-202721] JAM2 binds JAM3 - Mus musculus [Reaction:R-MMU-202706] Integrin alpha4beta1 binds JAM2:JAM3 - Mus musculus [Reaction:R-MMU-9679740] ITGA4:ITGB1 binds natalizumab - Mus musculus [Reaction:R-MMU-202726] F11R dimerises - Mus musculus [Reaction:R-MMU-202718] Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) - Mus musculus [Reaction:R-MMU-202704] Integrin alphaXbeta2 binds JAM3 - Mus musculus [Reaction:R-MMU-202710] MERTK receptor binds ligands (Gas6 or Protein S) - Mus musculus [Reaction:R-MMU-202713] CD84 homodimerises - Mus musculus [Reaction:R-MMU-2870221] E-selectin binds E-selectin ligand - Mus musculus [Reaction:R-MMU-202724] P-selectin binds P-selectin ligand - Mus musculus [Reaction:R-MMU-202709] JAM2 dimerises - Mus musculus [Reaction:R-MMU-202731] JAM3 dimerises - Mus musculus [Reaction:R-MMU-202702] CD177 binds PECAM-1 - Mus musculus [Reaction:R-MMU-202703] CD47 binds SIRP - Mus musculus [Reaction:R-MMU-202722] CD48 binds CD244 - Mus musculus [Reaction:R-MMU-202723] Integrin alpha5beta1 binds FN1 dimer - Mus musculus [Reaction:R-MMU-199093] CXADR binds to AMICA1 - Mus musculus [Reaction:R-MMU-141040] Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C - Mus musculus [Reaction:R-MMU-203130] OLR1 binds to oxidized LDL - Mus musculus [Reaction:R-MMU-203156] Platelet-derived TREM-1 ligand binds to TREM-1 - Mus musculus [Pathway:R-MMU-210993] Tie2 Signaling - Mus musculus [Pathway:R-MMU-210990] PECAM1 interactions - Mus musculus [Pathway:R-MMU-210991] Basigin interactions - Mus musculus [Reaction:R-MMU-202717] Heterodimerization of CEACAMs - Mus musculus [Reaction:R-MMU-5676133] CD74 binds MIF - Mus musculus [Reaction:R-MMU-8858428] FCAMR binds IgA - Mus musculus [Reaction:R-MMU-8867240] EPCAM binds itself to form homotypic cell adhesion - Mus musculus [Reaction:R-MMU-5635741] TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 - Mus musculus
inferredFrom	[Pathway:R-HSA-202733] Cell surface interactions at the vascular wall - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Cell surface interactions at the vascular wall
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-202733
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-MMU-109582] Hemostasis
(hasEncapsulatedEvent)	[Pathway:R-MMU-5673001] RAF/MAP kinase cascade
(inferredTo)	[Pathway:R-HSA-202733] Cell surface interactions at the vascular wall

Cite Us!