Reactome | Calcineurin:Calmodulin (CaN:CaM) [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10046234] calmodulin-dependent protein phosphatase activity of Calcineurin:Calmodulin (CaN:CaM) [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-2685705] NFAT:CaN:CaM [cytosol] - Mus musculus
consumedByEvent	[Reaction:R-MMU-4551451] Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling - Mus musculus [BlackBoxEvent:R-MMU-2730849] Calcineurin binds and dephosphorylates NFAT - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10040496
displayName	Calcineurin:Calmodulin (CaN:CaM) [cytosol]
hasComponent	[Complex:R-MMU-2026003] PPP3CA,B:Calmodulin [cytosol] [Complex:R-MMU-2025906] Ppp3r1:Calcium [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2025947] Calcineurin:Calmodulin (CaN:CaM) [cytosol] - Homo sapiens
maxDepth	5
name	Calcineurin:Calmodulin (CaN:CaM)
producedByEvent	[Reaction:R-MMU-2730872] Activation of Calcineurin - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-2025947
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-MMU-2730849] Calcineurin binds and dephosphorylates NFAT [Reaction:R-MMU-4551451] Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling
(hasComponent)	[Complex:R-MMU-2685705] NFAT:CaN:CaM [cytosol] [Complex:R-MMU-2025899] Calcineurin:p-NFATC1,2,3 [cytosol] [Complex:R-MMU-4551448] NFATC1:CaN:CaM [cytosol]
(physicalEntity)	[CatalystActivity:10046234] calmodulin-dependent protein phosphatase activity of Calcineurin:Calmodulin (CaN:CaM) [cytosol]
(output)	[Reaction:R-MMU-2730872] Activation of Calcineurin
(inferredTo)	[Complex:R-HSA-2025947] Calcineurin:Calmodulin (CaN:CaM) [cytosol]