Reactome | NOX2 complex [phagocytic vesicle membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10029331] superoxide-generating NAD(P)H oxidase activity of NOX2 complex [phagocytic vesicle membrane]
compartment	[Compartment:1222693] phagocytic vesicle membrane
componentOf	[Complex:R-MMU-5668618] NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9014424] RAC2 binds effectors at the phagocytic vesicle membrane - Mus musculus [Reaction:R-MMU-5668605] RAC2:GTP binds NOX2 complex - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10029330
displayName	NOX2 complex [phagocytic vesicle membrane]
hasComponent	[Complex:R-MMU-1996225] flavocytochrome b558 catalytic core [phagocytic vesicle membrane] [EntityWithAccessionedSequence:R-MMU-1996220] phospho-Ncf1 [phagolysosome] [EntityWithAccessionedSequence:R-MMU-1996211] phospho-Ncf2 [phagolysosome] [EntityWithAccessionedSequence:R-MMU-1996221] phospho-p-T154,S315-NCF4 [phagolysosome]
inDisease	false
inferredFrom	[DefinedSet:R-HSA-5674231] RAC2 phagosome effectors [phagocytic vesicle membrane] - Homo sapiens [Complex:R-HSA-1996217] NOX2 complex [phagocytic vesicle membrane] - Homo sapiens
maxDepth	3
name	NOX2 complex
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-1996217
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-9014424] RAC2 binds effectors at the phagocytic vesicle membrane [Reaction:R-MMU-5668605] RAC2:GTP binds NOX2 complex
(inferredTo)	[DefinedSet:R-HSA-5674231] RAC2 phagosome effectors [phagocytic vesicle membrane] [Complex:R-HSA-1996217] NOX2 complex [phagocytic vesicle membrane]
(physicalEntity)	[CatalystActivity:10029331] superoxide-generating NAD(P)H oxidase activity of NOX2 complex [phagocytic vesicle membrane]
(hasComponent)	[Complex:R-MMU-5668618] NOX2 complex:RAC2:GTP [phagocytic vesicle membrane]