Reactome | VEGF ligand-receptor interactions

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10099675
displayName	VEGF ligand-receptor interactions
eventOf	[Pathway:R-MMU-194138] Signaling by VEGF - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:180] vascular endothelial growth factor receptor signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-195378] Homodimerization of VEGF proteins - Mus musculus [Pathway:R-MMU-195399] VEGF binds to VEGFR leading to receptor dimerization - Mus musculus
inferredFrom	[Pathway:R-HSA-194313] VEGF ligand-receptor interactions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	VEGF ligand-receptor interactions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-194313
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-194138] Signaling by VEGF
(inferredTo)	[Pathway:R-HSA-194313] VEGF ligand-receptor interactions

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