Reactome | PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10000210] guanyl-nucleotide exchange factor activity of PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10000207
displayName	PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane]
hasComponent	[Complex:R-MMU-109797] GRB2-1:SOS1 [cytosol] [Complex:R-MMU-186811] PDGF:Phospho-PDGF receptor dimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-186827] PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] - Homo sapiens
maxDepth	5
memberOf	[DefinedSet:R-MMU-5672601] RAS GEFs [plasma membrane] - Mus musculus
name	PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1
producedByEvent	[Reaction:R-MMU-186826] GRB2:SOS1 complex binds to the active receptor - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-186827
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10000210] guanyl-nucleotide exchange factor activity of PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane]
(output)	[Reaction:R-MMU-186826] GRB2:SOS1 complex binds to the active receptor
(hasMember)	[DefinedSet:R-MMU-5672601] RAS GEFs [plasma membrane]
(inferredTo)	[Complex:R-HSA-186827] PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane]

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