Reactome | EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9999748] transmembrane receptor protein tyrosine kinase activity of EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-MMU-177930] GAB1 phosphorylation by EGFR kinase - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9999747
displayName	EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]
hasComponent	[Complex:R-MMU-9624425] EGF-like ligands:p-6Y EGFR dimer [plasma membrane] [DefinedSet:R-MMU-9038397] GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-180348] EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] - Homo sapiens
maxDepth	5
name	EGF-like ligands:p-6Y-EGFR:GRB2:GAB1
producedByEvent	[Reaction:R-MMU-177941] GRB2:GAB1 binds to phosphorylated EGFR - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-180348
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-MMU-177941] GRB2:GAB1 binds to phosphorylated EGFR
(input)	[Reaction:R-MMU-177930] GAB1 phosphorylation by EGFR kinase
(physicalEntity)	[CatalystActivity:9999748] transmembrane receptor protein tyrosine kinase activity of EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]
(inferredTo)	[Complex:R-HSA-180348] EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane]

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